GO:0038061 biological_process NIK/NF-kappaB signaling
| PAG Title | GO:0038061 biological_process NIK/NF-kappaB signaling |
| PAG ID | TAX023476 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | The process in which a signal is passed on to downstream components within the cell through the NIK-dependent processing and activation of NF-KappaB. Begins with activation of the NF-KappaB-inducing kinase (NIK), which in turn phosphorylates and activates IkappaB kinase alpha (IKKalpha). IKKalpha phosphorylates the NF-Kappa B2 protein (p100) leading to p100 processing and release of an active NF-KappaB (p52). |
| Species | Homo sapiens |
| nCoCo Score | 1,943 |
| Base PAG ID | TAX023476 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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